Strain Specificity and Production of Antibiotic Substances: III. Penicillium Notatum--Chrysogenum Group

A Comparison of Penicillin-producing Strains of Penicillium notatum-chrysogenum.

Sampling and storage. The fermentations were conducted in the 100-gallon tanks described by Stefaniak et al. (1946). Samples were removed periodically into 500-ml flasks and ifitered. A 0.5-ml filtered sample was immediately diluted for penicillin assay by addition to previously chilled phosphate buffer in volumetric flasks (4.0 g KH2P04 and 1.0 g K2HPO4 per 500 ml solution in distilled water; ...

Strain Specificity and Production of Antibiotic Substances. X. Characterization and Classification of Species within the Streptomyces Griseus Group.

Production of Calcium Gluconate by Penicillium chrysogenum

AMBEKAR, G. R. (Hindustan Antibiotics Ltd., Pimpri, India), S. B. THADANI, AND V. M. DOCTOR_ Production of calcium gluconate by Penicillium chrysogenum in submerged culture. Appl. Microbiol. 13:713-719. 1965.-The waste mycelium of Penicillium chrysogenum HA-10 (obtained at the end of penicillin fermentation), or a 24hr-old freshly grown vegetative inoculum of this organism, was found to utilize...

Organophosphonate Utilization by the Wild-Type Strain of Penicillium notatum.

We studied the biodegradation of compounds containing phosphorus-to-carbon bonds by using a wild-type strain of Penicillium notatum. The substrate specificity of this strain was studied, and we found that it is able to utilize structurally diverse organophosphonates as sole sources of phosphorus. This ability seems to be inducible, as indicated by the presence of a lag phase during growth. A po...

Microbiological Aspects of Penicillin: III. Production of Penicillin in Surface Cultures of Penicillium notatum.

Steadily increasing interest in penicillin as a chemotherapeutic agent has led to a parallel increase in the demand for penicillin for clinical application and chemical studies. Penicillin is produced in minute quantities by Penicillium notatum so that filtrates from the mold represent exceedingly dilute solutions of penicillin from which the active agent is extracted. The magnitude of the prob...